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김지혜 ( Kim Ji-Hye ) - 서울아산병원
서은지 ( Seo Eun-Ji ) - 서울아산병원
박희정 ( Park Hee-Jung ) - 서울아산병원
김시현 ( Kim Si-Hyeon ) - 서울아산병원
민자 ( Min Ja ) - 서울아산병원
박정윤 ( Park Jeong-Yun ) - 울산대학교 의과대학 임상전문간호학
김송철 ( Kim Song-Cheol ) - 울산대학교 의과대학 서울아산병원 외과
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Abstract
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Purpose: The purpose of this study was to compare the effectiveness of heparin and 0.9% normal saline solution
flushing for maintaining patency of nontunneled central venous catheters in patients with surgery.
Methods: A randomized controlled clinical trial was performed. Fiftyeight patients were prospectively enrolled and
fifty-four patients were completed the study. The heparin group consisted of 30 patients given 100u/ml diluted heparin flushing and the normal saline group consisted of 24 patients with 0.9% sodium chloride flushing.
Results: There was no significantly difference in occlusion between the heparin group and the normal saline group in nontunneled central venous catheters’ occlusion. Also there was no difference between these two groups in catheterrelated infections.
Conclusion: Flushing with 0.9% normal saline is as effective as flushing with heparin solution in maintaining the patency of nontunneled central venous catheters. In this study, however, the duration of central line use was short and the infection occurrence was little. Further studies are warranted with a larger sample size at multiple centers.
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KeyWords
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중심정맥관, 헤파린, 생리식염수, 폐색, 감염
Central venous catheters, Heparin, Sodium chloride, Catheter obstruction, Infection
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원문 및 링크아웃 정보
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등재저널 정보
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